Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.41 |
| ▸ | GABRP | O00591 | 4/20 | 0.41 |
| ▸ | GABRD | O14764 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128427 | 0.87 | ALDH1A1 (0.50) | CYP1A2MAPTTSHRALDH1A1POLB | |
| SCHEMBL127796 | 0.84 | TSHR (0.53) | CYP1A2MAPTTSHRALDH1A1POLB | |
| SCHEMBL128329 | 0.80 | MAPK1 (0.42) | CYP1A2MAPTTSHRCA12CA1 | |
| SCHEMBL128143 | 0.76 | ALDH1A1 (0.47) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL1815292 | 0.76 | HPGDS (0.40) | MAPTTSHRCA12CA1CA2 | |
| SCHEMBL1478915 | 0.76 | CYP1A2 (1.00) | CYP1A2MAPTTSHRCA12CA1 | |
| SCHEMBL27517498 | 0.74 | CYP1A2 (0.49) | CYP1A2MAPTTSHRCA12CA1 | |
| SCHEMBL7453186 | 0.72 | CYP1A2 (0.47) | CYP1A2MAPTTSHRCA12CA1 | |
| SCHEMBL27229504 | 0.72 | CYP1A2 (0.51) | CYP1A2MAPTTSHRCA12CA1 | |
| SCHEMBL4916148 | 0.72 | CYP1A2 (0.51) | CYP1A2MAPTTSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174672-A1 | Spirocycle Containing Pyridone Compounds | PROTEGO BIOPHARMA, INC. | 2024-05-30 | — | — | US | claimed |
| WO-2024092037-A1 | SPIROCYCLE CONTAINING PYRIDONE COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2024-05-02 | — | — | WO | claimed |
| CN-109071506-B | Substituted 2- (hetero) arylimidazolyl carboxamides as pest control agents | 拜耳作物科学股份公司 | 2021-03-02 | — | — | CN | claimed |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-28 | — | — | US | claimed |
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-14 | — | — | US | claimed |
| EP-3414236-A1 | SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-12-19 | — | — | EP | claimed |
| WO-2017137338-A1 | SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-17 | — | — | WO | claimed |
| US-20240174672-A1 | Spirocycle Containing Pyridone Compounds | PROTEGO BIOPHARMA, INC. | 2024-05-30 | — | — | US | disclosed |
| WO-2024092037-A1 | SPIROCYCLE CONTAINING PYRIDONE COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| US-20220192185-A1 | STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE | BASF SE (DE) | 2022-06-23 | — | — | US | disclosed |
| US-20220183278-A1 | STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA | BASF SE (DE) | 2022-06-16 | — | — | US | disclosed |
| US-20220159957-A1 | STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN | BASF SE (DE) | 2022-05-26 | — | — | US | disclosed |
| EP-3962269-A1 | STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN | BASF SE (DE) | 2022-03-09 | — | — | EP | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| EP-0920426-B9 | NEW THIAZOLE DERIVATIVES WITH PHOSPHODIESTERASE-INHIBITING EFFECT | ALTANA PHARMA AG (DE) | 2005-04-06 | — | — | EP | disclosed |
| EP-0920426-B1 | NEW THIAZOLE DERIVATIVES WITH PHOSPHODIESTERASE-INHIBITING EFFECT | ALTANA PHARMA AG (DE) | 2003-10-01 | — | — | EP | disclosed |
| US-6011037-A | Thiazole derivatives with phosphodiesterase-inhibiting action | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-01-04 | — | — | US | disclosed |
| EP-0247381-B1 | 5-FLUROROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5047521-A | Anticarcinogenic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | CYP1A2 15/4885MAPT 4737/4885TSHR 1122/4885 |
| US-20220159957-A1 | STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN | ERO1A, ERLIN2, ERLIN1 | CYP1A2 345/4885MAPT 1368/4885TSHR 3813/4885 |
| US-20220192185-A1 | STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE | LSS, STS, U2SURP | CYP1A2 657/4885MAPT 1851/4885TSHR 4730/4885 |
| US-20240174672-A1 | Spirocycle Containing Pyridone Compounds | TTR, BCL6, PLPBP | CYP1A2 2090/4885MAPT 100/4885TSHR 3699/4885 |
| US-20220183278-A1 | STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA | RCC1, SAMM50, PIGS | CYP1A2 1664/4885MAPT 695/4885TSHR 4520/4885 |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | CYP1A2 15/4885MAPT 4737/4885TSHR 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.