Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115918 | 0.84 | FFAR1 (0.52) | MAOAKDM1AMAOBVNN1ERCC1 | |
| SCHEMBL28471333 | 0.75 | LMNA (0.49) | MAOAKDM1AMAOBVNN1ALDH1A1 | |
| SCHEMBL25588020 | 0.74 | KDM1A (0.51) | MAOAKDM1AMAOBVNN1ERCC1 | |
| SCHEMBL320058 | 0.74 | LOXL2 (0.59) | MAOAKDM1AMAOBVNN1MAPT | |
| SCHEMBL30471916 | 0.74 | LOXL2 (0.59) | MAOAKDM1AMAOBVNN1MAPT | |
| SCHEMBL3461756 | 0.74 | ERCC1 (0.60) | MAOAKDM1AMAOBVNN1ERCC1 | |
| SCHEMBL5106820 | 0.74 | ERCC1 (0.44) | VNN1ERCC1ERCC4LMNAFFAR1 | |
| SCHEMBL13181742 | 0.73 | KDM1A (0.50) | MAOAKDM1AMAOBVNN1ERCC1 | |
| SCHEMBL4723260 | 0.73 | CYP3A4 (0.53) | MAOAKDM1AMAOBVNN1MAPT | |
| SCHEMBL2774523 | 0.72 | FFAR1 (0.52) | MAOAKDM1AMAOBVNN1ERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240308984-A1 | Jak Inhibitor With High Oral Bioavailability | TECHNODERMA MEDICINES INC (CN) | 2024-09-19 | — | — | US | disclosed |
| EP-4382522-A1 | JAK INHIBITOR WITH HIGH ORAL BIOAVAILABILITY | Technoderma Medicines Inc. (CN) | 2024-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240308984-A1 | Jak Inhibitor With High Oral Bioavailability | JAK1, JAK2, JAK3 | MAOA 3651/4885KDM1A 361/4885MAOB 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.