Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29810725 | 0.81 | BRD9 (0.36) | TDP2BRD9RXFP1METAP1HSP90AA1 | |
| SCHEMBL29842864 | 0.77 | BRD9 (0.39) | TDP2BRD9RXFP1METAP1HSP90AA1 | |
| SCHEMBL25897313 | 0.77 | BRD9 (0.39) | TDP2BRD9RXFP1METAP1HSP90AA1 | |
| SCHEMBL25897321 | 0.72 | MEN1 (0.39) | BRD9RXFP1METAP1ALDH1A1HSP90AA1 | |
| SCHEMBL25897332 | 0.72 | BRD9 (0.36) | TDP2BRD9RXFP1METAP1HSP90AA1 | |
| SCHEMBL25574384 | 0.69 | MAP3K5 (0.50) | BRD9IDO1 | |
| SCHEMBL27238487 | 0.69 | ADRA2A (0.35) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL27238486 | 0.69 | HSD17B10 (0.34) | ALDH1A1KMT2ALMNAMEN1TSHR | |
| SCHEMBL16745998 | 0.69 | TDP2 (0.42) | TDP2BRD9ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL30317135 | 0.69 | MRGPRX1 (0.46) | BRD9RXFP1ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240189309-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2024-06-13 | — | — | US | disclosed |
| WO-2022175745-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240189309-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK2, JAK1 | TDP2 173/4885BRD9 430/4885RXFP1 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.