Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18581920 | 1.00 | POLB (0.34) | POLBPPM1DMEN1KMT2ABUB1 | |
| SCHEMBL18581922 | 1.00 | POLB (0.34) | POLBPPM1DMEN1KMT2ABUB1 | |
| SCHEMBL449025 | 0.85 | CHRM2 (0.35) | MEN1KMT2A | |
| SCHEMBL433223 | 0.85 | CHRM2 (0.35) | MEN1KMT2A | |
| SCHEMBL2133453 | 0.85 | CHRM2 (0.35) | MEN1KMT2A | |
| SCHEMBL28522830 | 0.78 | APEX1 (0.35) | POLBPPM1D | |
| SCHEMBL28522829 | 0.78 | APEX1 (0.35) | POLBPPM1D | |
| SCHEMBL28532943 | 0.78 | APEX1 (0.35) | POLBPPM1D | |
| SCHEMBL17848943 | 0.78 | SMN1; SMN2 (0.36) | POLBPPM1D | |
| SCHEMBL8541759 | 0.78 | HPGD (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396469-A | Inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| EP-2447265-A1 | NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2012-05-02 | — | — | EP | disclosed |