Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PPM1D | O15297 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522830 | 1.00 | APEX1 (0.35) | APEX1BLMPPM1DPOLBTP53 | |
| SCHEMBL28532943 | 1.00 | APEX1 (0.35) | APEX1BLMPPM1DPOLBTP53 | |
| SCHEMBL28535101 | 0.86 | LMNA (0.38) | APEX1BLMPPM1DTP53SMN1; SMN2 | |
| SCHEMBL21389110 | 0.86 | LMNA (0.38) | APEX1BLMPPM1DTP53SMN1; SMN2 | |
| SCHEMBL28527501 | 0.86 | LMNA (0.38) | APEX1BLMPPM1DTP53SMN1; SMN2 | |
| SCHEMBL35210460 | 0.82 | PPM1D (0.32) | PPM1DSMN1; SMN2 | |
| SCHEMBL30752652 | 0.82 | PPM1D (0.32) | PPM1DSMN1; SMN2 | |
| SCHEMBL21389421 | 0.82 | BRD4 (0.33) | PPM1D | |
| SCHEMBL28537661 | 0.82 | BRD4 (0.33) | PPM1D | |
| SCHEMBL21389115 | 0.79 | PLA2G7 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236161-A | Modulators of G protein-coupled receptors | 卡莫特治疗学股份有限公司 | 2021-01-15 | — | — | CN | disclosed |