Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 14/20 | 0.34 |
| ▸ | CDK8 | P49336 | 14/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 14/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 9/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890501 | 0.89 | CCNC (0.32) | CCNCCDK8HASPINCDK19BACE1 | |
| SCHEMBL27245043 | 0.83 | BACE1 (0.39) | BACE1 | |
| Hydrochloric Acid SCHEMBL27245163 | 0.82 | BACE1 (0.39) | BACE1 | |
| SCHEMBL27245044 | 0.79 | AKR1B1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL30890769 | 0.78 | AKR1B1 (0.41) | — | |
| SCHEMBL27245225 | 0.74 | GAA (0.33) | BACE1 | |
| SCHEMBL30890473 | 0.74 | GAA (0.33) | BACE1 | |
| SCHEMBL27245141 | 0.74 | OTUD7B (0.34) | BACE1 | |
| SCHEMBL30890445 | 0.74 | OTUD7B (0.34) | BACE1 | |
| SCHEMBL27244746 | 0.74 | NPC1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | CCNC 3701/4885CDK8 2171/4885HASPIN 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.