SCHEMBL27245162

SCHEMBL27245162

Cc1cnc2c(c1)NC(=O)[C@]1(C[C@@H](C#N)N(C(=O)[C@H](CC3CC3)N(C)C(=O)[C@H](CC3CC3)NC(=O)C(F)(F)F)C1)O2

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ OTUD7B Q6GQQ9 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27245169 1.00 OTUD7B (0.31) OTUD7B
SCHEMBL27245152 0.89 — —
SCHEMBL27245156 0.89 — —
SCHEMBL27245050 0.88 OTUD7B (0.31) OTUD7B
SCHEMBL27245055 0.88 OTUD7B (0.31) OTUD7B
SCHEMBL27245051 0.86 — —
SCHEMBL27245056 0.86 — —
SCHEMBL27245187 0.84 OTUD7B (0.30) OTUD7B
SCHEMBL27245177 0.83 CTSL (0.31) —
SCHEMBL27245183 0.83 CTSL (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199647-A1 ANTI-VIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199647-A1 ANTI-VIRAL COMPOUNDS EIF2AK2, ZC3HAV1, HAVCR2 OTUD7B 2426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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