Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27245240 | 1.00 | GRM6 (0.50) | GRM6CYP19A1ACES1PR1S1PR5 | |
| SCHEMBL8044487 | 1.00 | GRM6 (0.50) | GRM6CYP19A1ACES1PR1S1PR5 | |
| SCHEMBL22608279 | 0.84 | GRM6 (0.48) | GRM6CYP19A1ACES1PR1S1PR5 | |
| SCHEMBL29053804 | 0.84 | GRM6 (0.48) | GRM6CYP19A1ACES1PR1S1PR5 | |
| SCHEMBL29053803 | 0.84 | GRM6 (0.48) | GRM6CYP19A1ACES1PR1S1PR5 | |
| SCHEMBL13841904 | 0.84 | MMP2 (0.55) | CYP19A1KMT2AALDH1A1 | |
| SCHEMBL2821204 | 0.84 | MMP2 (0.55) | CYP19A1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28608849 | 0.83 | GRM6 (0.47) | GRM6CYP19A1ACES1PR1S1PR5 | |
| Hydrochloric Acid SCHEMBL28591031 | 0.83 | GRM6 (0.47) | GRM6CYP19A1ACES1PR1S1PR5 | |
| Hydrochloric Acid SCHEMBL28591027 | 0.83 | GRM6 (0.47) | GRM6CYP19A1ACES1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | GRM6 3791/4885CYP19A1 3784/4885ACE 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.