Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29053804 | 1.00 | GRM6 (0.48) | GRM6CYP19A1SIGMAR1ACES1PR1 | |
| SCHEMBL29053803 | 1.00 | GRM6 (0.48) | GRM6CYP19A1SIGMAR1ACES1PR1 | |
| Hydrochloric Acid SCHEMBL28591031 | 0.98 | GRM6 (0.47) | GRM6CYP19A1SIGMAR1ACES1PR1 | |
| Hydrochloric Acid SCHEMBL28591027 | 0.98 | GRM6 (0.47) | GRM6CYP19A1SIGMAR1ACES1PR1 | |
| Hydrochloric Acid SCHEMBL28608849 | 0.98 | GRM6 (0.47) | GRM6CYP19A1SIGMAR1ACES1PR1 | |
| SCHEMBL29053802 | 0.88 | LMNA (0.41) | CYP19A1SIGMAR1S1PR5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28591478 | 0.87 | LMNA (0.40) | CYP19A1SIGMAR1S1PR5ALDH1A1 | |
| SCHEMBL22608386 | 0.85 | FKBP1A (0.52) | CYP19A1SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL8044487 | 0.84 | GRM6 (0.50) | GRM6CYP19A1ACES1PR1S1PR5 | |
| SCHEMBL27245241 | 0.84 | GRM6 (0.50) | GRM6CYP19A1ACES1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135850-B | Preparation method of chiral oxo-azacycloalkane compound with high optical purity | 新发药业有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-113135850-B | Preparation method of chiral oxo-azacycloalkane compound with high optical purity | 新发药业有限公司 | 2023-08-22 | — | — | CN | disclosed |
| EP-3733648-B1 | METHOD FOR PREPARING 5R-BENZYLOXYAMINOPIPERIDIN-2S-CARBOXYLIC ACID OR DERIVATIVE THEREOF | XINFA PHARMACEUTICAL CO LTD (CN) | 2022-06-08 | — | — | EP | disclosed |
| US-20210323920-A1 | METHOD OF PREPARING 5R-[(BENZYLOXY) AMINO] PIPERIDINE-2S-CARBOXYLIC ACID OR A DERIVATIVE THEREOF | XINFA PHARMACEUTICAL CO., LTD (CN) | 2021-10-21 | — | — | US | disclosed |
| US-11142499-B1 | Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof | XINFA PHARMACEUTICAL CO., LTD (CN) | 2021-10-12 | — | — | US | disclosed |
| CN-109970625-B | Preparation method of 5R-benzyloxyaminopiperidine-2S-formic acid or derivative thereof | 新发药业有限公司 | 2021-02-26 | — | — | CN | disclosed |
| EP-3733648-A1 | METHOD FOR PREPARING 5R-BENZYLOXYAMINOPIPERIDIN-2S-CARBOXYLIC ACID OR DERIVATIVE THEREOF | Xinfa Pharmaceutical Co., Ltd (CN) | 2020-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142499-B1 | Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof | GLUL, GRIN2D, GRIN2C | GRM6 126/4885CYP19A1 4429/4885SIGMAR1 3061/4885 |
| US-20210323920-A1 | METHOD OF PREPARING 5R-[(BENZYLOXY) AMINO] PIPERIDINE-2S-CARBOXYLIC ACID OR A DERIVATIVE THEREOF | GLUL, GRIN2D, GRIN2C | GRM6 126/4885CYP19A1 4429/4885SIGMAR1 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.