Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 9/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29972597 | 1.00 | RYR2 (0.44) | RYR2ABHD6ESR1ESR2KCNH2 | |
| SCHEMBL29972813 | 0.87 | ABHD6 (0.45) | RYR2ABHD6ESR1ESR2KCNH2 | |
| SCHEMBL24761127 | 0.87 | ABHD6 (0.45) | RYR2ABHD6ESR1ESR2KCNH2 | |
| SCHEMBL30850852 | 0.84 | RYR2 (0.44) | RYR2ABHD6 | |
| SCHEMBL30850927 | 0.81 | RYR2 (0.37) | RYR2ABHD6SLC6A9KDM4E | |
| SCHEMBL26607680 | 0.79 | RAB9A (0.41) | ABHD6KDM4E | |
| SCHEMBL21591731 | 0.76 | ABHD6 (0.59) | ABHD6KCNH2KDM4E | |
| SCHEMBL15880544 | 0.74 | ESR1 (0.57) | RYR2ABHD6ESR1ESR2 | |
| SCHEMBL30677763 | 0.74 | ESR1 (0.57) | RYR2ABHD6ESR1ESR2 | |
| SCHEMBL31013839 | 0.74 | ABHD6 (0.39) | ABHD6SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808102-B | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2021-12-31 | — | — | CN | claimed |
| CN-111808102-A | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2020-10-23 | — | — | CN | claimed |
| US-20250108123-A1 | COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2025-04-03 | — | — | US | disclosed |
| US-20240199548-A1 | NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-06-20 | — | — | US | disclosed |
| CN-111808102-B | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-111808102-A | 3-methoxy-6, 7-dihydro-5H-pyrrolo [3,4-b ] pyridine hydrochloride and synthetic method thereof | 南通大学 | 2020-10-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199548-A1 | NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | STING1, IRF3, CGAS | RYR2 1921/4885ABHD6 4080/4885ESR1 4028/4885 |
| US-20250108123-A1 | COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | STING1, IRF3, CGAS | RYR2 2941/4885ABHD6 3346/4885ESR1 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.