Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.78 |
| ▸ | HTR1A | P08908 | 4/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | DRD1 | P21728 | 1/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678268 | 0.92 | HTR1A (0.78) | HTR7HTR1AABCB11ADRA2AADORA3 | |
| SCHEMBL8943053 | 0.89 | HTR1A (0.86) | HTR7HTR1AABCB11ADRA2AADORA3 | |
| SCHEMBL8121534 | 0.88 | HTR1A (0.88) | HTR7HTR1AABCB11ADRA2AADORA3 | |
| SCHEMBL12124676 | 0.87 | HTR7 (0.82) | HTR7HTR1A | |
| SCHEMBL27031059 | 0.87 | HTR7 (0.84) | HTR7HTR1AADORA3CHRM1SLC6A4 | |
| SCHEMBL8135691 | 0.86 | HTR7 (1.00) | HTR7HTR1AABCB11ADRA2AADORA3 | |
| SCHEMBL27031076 | 0.86 | HTR7 (0.83) | HTR7HTR1AP2RX7LMNADRD2 | |
| SCHEMBL8121051 | 0.85 | HTR1A (0.88) | HTR7HTR1AABCB11ADRA2AADORA3 | |
| SCHEMBL27246583 | 0.83 | HTR7 (0.68) | HTR7HTR1AABCB11ADRA2AADORA3 | |
| SCHEMBL27031058 | 0.82 | HTR7 (0.76) | HTR7HTR1AP2RX7LMNADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199555-A1 | APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HT7 RECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION | Université d'Orléans (FR) | 2024-06-20 | — | — | US | disclosed |
| EP-4308119-A1 | <SUP2/>? <SUB2/>?7?APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HTRECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION | Centre National de la Recherche Scientifique (FR) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022195102-A1 | APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HT7 RECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199555-A1 | APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HT7 RECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION | HTR7, HTR1A, CNR1 | HTR7 1/4885HTR1A 2/4885ABCB11 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.