Sugi Predict

Sugi Predict / Compounds / SCHEMBL2724904

SCHEMBL2724904

SCHEMBL2724904

Fc1cc(-c2c3ccccc3c(-c3ccccc3)c3c(F)ccc(F)c23)cc(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 3/20 0.40
▸ CYP3A4 P08684 3/20 0.40
▸ CYP2C9 P11712 3/20 0.40
▸ CYP2C19 P33261 3/20 0.40
▸ MAP2 P11137 2/20 0.33
▸ POLB P06746 2/20 0.33
▸ ACHE P22303 2/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ AR P10275 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ ESR1 P03372 3/20 0.33
▸ ESR2 Q92731 3/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2724460 0.94 CCNE2 (0.34) CYP1A2CYP3A4CYP2C9CYP2C19CCNE2
SCHEMBL2726055 0.90 CYP1A2 (0.46) CYP1A2CYP3A4CYP2C9CYP2C19MAP2
SCHEMBL2726216 0.89 CYP1A2 (0.36) CYP1A2CYP3A4CYP2C9CYP2C19MAP2
SCHEMBL2728156 0.89 LMNA (0.40) CYP1A2CYP3A4CYP2C9CYP2C19MAP2
SCHEMBL2711234 0.88 ACHE (0.41) CYP1A2CYP3A4CYP2C9CYP2C19MAP2
SCHEMBL2725920 0.88 CYP1A2 (0.47) CYP1A2CYP3A4CYP2C9CYP2C19MAP2
SCHEMBL12086058 0.87 NPC1 (0.33) LMNAALDH1A1CCNE2CDK4CCND1
SCHEMBL2726253 0.87 CYP1A2 (0.35) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL2941870 0.87 CYP1A2 (0.33) CYP1A2CYP3A4CYP2C9CYP2C19CCNE2
SCHEMBL2725664 0.87 CYP1A2 (0.42) CYP1A2CYP3A4CYP2C9CYP2C19MAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 — — EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 — — US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 — — US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 — — EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 — — US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 — — US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 CYP1A2 22/4885CYP3A4 18/4885CYP2C9 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.