Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621588 | 0.92 | KDM4E (0.55) | KDM4EKMT2APDGFRBPDGFRAMAPT | |
| SCHEMBL14582923 | 0.79 | ESR2 (0.48) | KDM4EKMT2APDGFRBPDGFRAMAPT | |
| SCHEMBL20774316 | 0.77 | PDGFRB (0.36) | KDM4EPDGFRBPDGFRAALDH1A1 | |
| SCHEMBL1258593 | 0.76 | ALDH1A1 (0.52) | KDM4EKMT2APDGFRBPDGFRAMAPT | |
| SCHEMBL8530324 | 0.76 | HRH4 (0.47) | KDM4EKMT2APDGFRBPDGFRAMAPT | |
| SCHEMBL1128647 | 0.76 | PABPC1 (0.44) | KMT2ABACE1MEN1HTTCYP1A2 | |
| SCHEMBL15688492 | 0.76 | KDM4E (0.46) | KDM4EKMT2APDGFRBPDGFRAMAPT | |
| SCHEMBL29880393 | 0.76 | BACE1 (0.55) | KDM4EKMT2APDGFRBPDGFRAMAPT | |
| SCHEMBL101566 | 0.76 | KMT2A (0.48) | KDM4EKMT2APDGFRBPDGFRABACE1 | |
| SCHEMBL30665754 | 0.76 | HRH4 (0.47) | KDM4EKMT2APDGFRBPDGFRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052556-A1 | NOVEL HALOALKOXYQUINAZOLINES, AND PREPARATION AND USE THEREOF | UNIVERSITÄT LEIPZIG (DE) | 2012-04-26 | — | — | WO | disclosed |
| US-4582526-A | Carbamic acid ester herbicides | HOFFMANN-LA ROCHE INC. (US) | 1986-04-15 | — | — | US | disclosed |