Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27249553 | 0.85 | LMNA (0.55) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL27249555 | 0.81 | HTT (0.57) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL27249698 | 0.77 | ALDH1A1 (0.66) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL27249546 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL27249503 | 0.77 | NR4A2 (0.47) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL3456294 | 0.76 | CNR1 (0.60) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL3457429 | 0.76 | ALDH1A1 (0.68) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL23940225 | 0.75 | HDAC6 (0.56) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL27249504 | 0.75 | POLB (0.54) | ALDH1A1LMNAMITFMAPTKMT2A | |
| SCHEMBL27249727 | 0.74 | HDAC6 (0.54) | ALDH1A1LMNAMITFMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077391-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2024-04-18 | — | — | WO | disclosed |