SCHEMBL2724993

SCHEMBL2724993

COc1c(F)c(F)c(-c2c3ccccc3c(-c3ccc(F)cc3F)c3c(F)ccc(F)c23)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 4/20 0.36
FABP5 Q01469 4/20 0.36
MAPK14 Q16539 2/20 0.33
F2RL3 Q96RI0 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FABP3 P05413 1/20 0.32
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
TRPA1 O75762 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
TUBB4A P04350 3/20 0.31
TUBB P07437 3/20 0.31
TUBA3C P0DPH7 3/20 0.31
TUBA1B P68363 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2724677 0.92 FABP4 (0.34) FABP4FABP5MAPK14F2RL3KDM4E
SCHEMBL2726656 0.92 F2RL3 (0.33) FABP4FABP5MAPK14F2RL3
SCHEMBL2710688 0.90 MAPK14 (0.34) FABP4FABP5MAPK14F2RL3KDM4E
SCHEMBL2725759 0.90 MAPK14 (0.34) FABP4FABP5MAPK14F2RL3
SCHEMBL2710873 0.89 FABP4 (0.36) FABP4FABP5MAPK14F2RL3KDM4E
SCHEMBL2727184 0.87 ALDH1A1 (0.33) FABP4FABP5MAPK14ALDH1A1ALOX5AP
SCHEMBL2725037 0.86 KDM4E (0.43) KDM4EALDH1A1MAPK1SMN1; SMN2ALOX5AP
SCHEMBL2710206 0.85 FABP4 (0.35) FABP4FABP5MAPK14F2RL3KDM4E
SCHEMBL2726996 0.85 FABP4 (0.35) FABP4FABP5MAPK14F2RL3KDM4E
SCHEMBL2727925 0.84 ALDH1A1 (0.42) KDM4EALDH1A1MAPK1SMN1; SMN2ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 FABP4 396/4885FABP5 309/4885MAPK14 3742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.