SCHEMBL2725009

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2725870	0.83	CYP3A4 (0.57)	CSF1RCYP3A4CYP2C9LRRK2
	SCHEMBL2723899	0.82	CYP3A4 (0.62)	KDM4EALDH1A1SMN1; SMN2RXFP1CSF1R
	SCHEMBL2724054	0.82	CYP3A4 (0.59)	CSF1RCYP3A4CYP2C9PDE4BLRRK2
	SCHEMBL6391519	0.79	CYP3A4 (0.52)	CSF1RCYP3A4CYP2C9LRRK2
	SCHEMBL6394363	0.77	KDM4E (0.43)	KDM4EALDH1A1SMN1; SMN2RXFP1CSF1R
	SCHEMBL2725774	0.77	CREBBP (0.49)	KDM4EALDH1A1SMN1; SMN2RXFP1CSF1R
	SCHEMBL2723445	0.76	CYP3A4 (0.56)	KDM4EALDH1A1SMN1; SMN2RXFP1CSF1R
	SCHEMBL6395157	0.76	LDHA (0.61)	KDM4EALDH1A1SMN1; SMN2RXFP1CSF1R
	SCHEMBL2723596	0.75	CYP3A4 (0.53)	CSF1RCYP3A4CYP2C9LRRK2
	SCHEMBL2724622	0.74	CYP3A4 (0.57)	KDM4EALDH1A1SMN1; SMN2RXFP1CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.