Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.65 |
| ▸ | RXRB | P28702 | 10/20 | 0.65 |
| ▸ | RXRG | P48443 | 10/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989548 | 0.83 | GSK3B (0.69) | RXRARXRBRXRGPTPN1GSK3B | |
| SCHEMBL7997819 | 0.82 | PTPN1 (0.66) | PTPN1GSK3BCES2MMP1CES1 | |
| SCHEMBL15744633 | 0.81 | RXRA (0.71) | RXRARXRBRXRGCES2CES1 | |
| SCHEMBL31492946 | 0.81 | RXRA (0.61) | RXRARXRBRXRGPTPN1GSK3B | |
| SCHEMBL12819956 | 0.80 | SMN1; SMN2 (0.50) | PTPN1GSK3BMMP2MMP8 | |
| SCHEMBL23698041 | 0.79 | RXRA (1.00) | RXRARXRBRXRG | |
| SCHEMBL28731633 | 0.78 | RXRA (0.58) | RXRARXRBRXRGPTPN1GSK3B | |
| SCHEMBL12187543 | 0.75 | CES2 (0.50) | RXRARXRBRXRGCES2 | |
| SCHEMBL2389365 | 0.73 | RXRA (0.65) | RXRARXRBRXRG | |
| SCHEMBL13247925 | 0.73 | RXRA (0.59) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094566-A1 | INDACENE AND AZAINDACENE COMPOUNDS AND HIGHER HOMOLOGUES AND THE USE THEREOF | Credoxys GmbH (DE) | 2024-05-10 | — | — | WO | disclosed |