Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27250573 | 0.94 | MAPK1 (0.39) | MAPK1HTTPIK3CDPIK3CAMTOR | |
| SCHEMBL27250662 | 0.92 | MAPK1 (0.43) | MAPK1HTTPIK3CDPIK3CAMTOR | |
| SCHEMBL27250553 | 0.91 | PDE10A (0.35) | FLT3ESR1ESR2ALDH1A1CYP1A2 | |
| SCHEMBL27250555 | 0.90 | ESR1 (0.42) | FLT3ESR1ESR2ALDH1A1KDM4E | |
| SCHEMBL20736406 | 0.90 | MAPK1 (0.32) | MAPK1HTTCYP1A2PDE10A | |
| SCHEMBL20737184 | 0.89 | ESR1 (0.38) | MAPK1HTTFLT3ESR1ESR2 | |
| SCHEMBL27250429 | 0.88 | MAPK1 (0.40) | MAPK1HTTPIK3CDPIK3CAMTOR | |
| SCHEMBL20737172 | 0.88 | MAPK1 (0.42) | MAPK1HTTPIK3CDPIK3CAMTOR | |
| SCHEMBL20737752 | 0.87 | MAPK1 (0.41) | MAPK1HTTPIK3CDPIK3CAMTOR | |
| SCHEMBL27250554 | 0.87 | PDE10A (0.36) | MAPK1FLT3CYP1A2PDE10ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12022728-B2 | Organic electroluminescent element and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2024-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12022728-B2 | Organic electroluminescent element and electronic device | L1CAM, ESR1, LEF1 | MAPK1 499/4885HTT 2278/4885PIK3CD 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.