SCHEMBL20737172

SCHEMBL20737172

Cc1nc2ccccc2n1-c1ccc(-c2cc3c(c4ccccc24)-c2ccc4ccccc4c2C32c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
FLT3 P36888 2/20 0.35
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD11B1 P28845 1/20 0.33
CYP1A2 P05177 1/20 0.33
PDE10A Q9Y233 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32
GSR P00390 1/20 0.32
MCHR1 Q99705 1/20 0.32
HSD17B10 Q99714 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20737162 0.90 PDE10A (0.36) MAPK1HTTFLT3ALDH1A1CYP1A2
SCHEMBL20737174 0.90 ESR1 (0.44) FLT3ALDH1A1KDM4E
SCHEMBL20737226 0.89 ESR1 (0.40) MAPK1HTTFLT3ALDH1A1POLB
SCHEMBL27250488 0.89 MAPK1 (0.43) MAPK1HTTFLT3NR1H2NR1H3
SCHEMBL27250552 0.88 MAPK1 (0.40) MAPK1HTTFLT3NR1H2NR1H3
SCHEMBL20737153 0.87 CYP1A2 (0.38) MAPK1FLT3CYP1A2PDE10ASMN1; SMN2
SCHEMBL20737204 0.87 MAPK1 (0.43) MAPK1HTTFLT3NR1H2NR1H3
SCHEMBL20737221 0.85 ALDH1A1 (0.43) MAPK1HTTFLT3ALDH1A1KDM4E
SCHEMBL27250662 0.85 MAPK1 (0.43) MAPK1HTTFLT3NR1H2NR1H3
SCHEMBL20737701 0.84 ESR1 (0.39) MAPK1HTTFLT3ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022728-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-06-25 US disclosed
US-11552251-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552251-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 MAPK1 499/4885HTT 2278/4885FLT3 3632/4885
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, ESR1, LEF1 MAPK1 499/4885HTT 2278/4885FLT3 3632/4885
US-12022728-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 MAPK1 499/4885HTT 2278/4885FLT3 3632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.