SCHEMBL27253199

SCHEMBL27253199

c1ccc(-c2cccc(N(c3ccccc3)c3ccc4oc5cc(-c6ccc7c(c6)oc6c(-c8ccc9oc%10ccccc%10c9c8)cccc67)ccc5c4c3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.47
PRKDC P78527 2/20 0.43
GGPS1 O95749 1/20 0.39
MMP12 P39900 1/20 0.38
MMP13 P45452 1/20 0.38
PLA2G2A P14555 4/20 0.37
PLA2G4A P47712 4/20 0.37
PTGES2 Q9H7Z7 1/20 0.37
PLA2G10 O15496 1/20 0.36
HCRTR1 O43613 1/20 0.34
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
AHR P35869 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27253284 1.00 ALOX5 (0.47) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL25621656 0.97 ALOX5 (0.45) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL27252732 0.97 ALOX5 (0.50) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL27252688 0.97 ALOX5 (0.50) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL27252727 0.97 ALOX5 (0.50) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL27252774 0.97 ALOX5 (0.50) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL25621406 0.96 ALOX5 (0.46) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL17153426 0.96 ALOX5 (0.51) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL10110702 0.96 ALOX5 (0.51) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL19543760 0.96 ALOX5 (0.51) ALOX5PRKDCGGPS1MMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014716-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2024-01-18 WO disclosed