SCHEMBL19543760

SCHEMBL19543760

c1ccc(-c2cccc(N(c3ccccc3)c3ccc(-c4ccc5c(c4)oc4cc(-c6cccc7c6oc6ccccc67)ccc45)cc3)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
PRKDC P78527 5/20 0.46
GGPS1 O95749 1/20 0.42
MMP12 P39900 1/20 0.40
MMP13 P45452 1/20 0.40
PTGES2 Q9H7Z7 1/20 0.39
HCRTR1 O43613 1/20 0.36
AHR P35869 2/20 0.35
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
ATM Q13315 2/20 0.33
PLA2G10 O15496 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19543748 0.98 ALOX5 (0.48) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL27253199 0.96 ALOX5 (0.47) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL27253284 0.96 ALOX5 (0.47) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL17705901 0.95 ALOX5 (0.51) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL27252689 0.95 ALOX5 (0.53) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL19444961 0.95 ALOX5 (0.53) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL17705902 0.95 ALOX5 (0.56) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL25621656 0.94 ALOX5 (0.45) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL24004261 0.94 ALOX5 (0.51) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL10307083 0.94 ALOX5 (0.51) ALOX5PRKDCGGPS1MMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 US disclosed
US-11316125-B2 Organic light-emitting device and display apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-26 US disclosed
US-20200111986-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-09 US disclosed
EP-3246963-A2 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-11-22 EP disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 ALOX5 2130/4885PRKDC 3792/4885GGPS1 902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.