Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 11/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 8/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726142 | 0.87 | BAZ2A (0.48) | CPT1ATRPV1BAZ2ACPT2CPT1B | |
| SCHEMBL2725756 | 0.84 | CPT1A (0.43) | CPT1ATRPV1BAZ2ACPT2CPT1B | |
| SCHEMBL6468162 | 0.83 | ALDH1A1 (0.44) | BAZ2AKMT2AHSD11B1 | |
| SCHEMBL5645605 | 0.80 | TRPV1 (0.46) | CPT1ATRPV1BAZ2ACPT2CPT1B | |
| SCHEMBL475512 | 0.80 | TRPV1 (0.46) | CPT1ATRPV1BAZ2ACPT2CPT1B | |
| SCHEMBL2728854 | 0.78 | TRPV1 (0.46) | CPT1ATRPV1BAZ2ACPT2CPT1B | |
| SCHEMBL27798798 | 0.76 | CPT1A (0.47) | CPT1ATRPV1BAZ2ACPT2CPT1B | |
| SCHEMBL27798797 | 0.76 | CPT1A (0.47) | CPT1ATRPV1BAZ2ACPT2CPT1B | |
| SCHEMBL2636237 | 0.74 | HSD11B1 (0.66) | CPT1ATRPV1CPT2CPT1BHSD11B1 | |
| SCHEMBL20742595 | 0.73 | PRCP (0.37) | CPT1ACPT2CPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |