SCHEMBL2725429

SCHEMBL2725429

CCCC(CCCCCCCCCC1CC(C)(C)N(C)C(C)(C)C1)OC(=O)CC(C(=O)O)C(CC(=O)O)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.31
MAPK1 P28482 2/20 0.30
CYP1A2 P05177 2/20 0.30
MEN1 O00255 1/20 0.30
GMNN O75496 1/20 0.30
LMNA P02545 1/20 0.30
HSP90AA1 P07900 1/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
TP53 P04637 1/20 0.30
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2725071 0.87 MAPK1 (0.31) MAPK1CYP1A2MEN1GMNNLMNA
SCHEMBL5190817 0.81 TDP1 (0.33) MAPK1MAPTNPSR1
SCHEMBL93527 0.78 TDP1 (0.31) GPR84TSHR
SCHEMBL2725425 0.78 GPR84 (0.38) GPR84MAPK1CYP1A2MEN1GMNN
SCHEMBL373325 0.75 GPR84 (0.34) GPR84
SCHEMBL373324 0.74 GPR84 (0.32) GPR84
SCHEMBL14840403 0.71 GPR84 (0.34) GPR84
SCHEMBL7931608 0.71 GPR84 (0.34) GPR84BLM
SCHEMBL5774736 0.70 TDP1 (0.40) MEN1LMNAKMT2ATSHR
SCHEMBL1543131 0.69 GPR84 (0.32) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2906621-B1 HETEROPHASIC POLYPROPYLENE COMPOSITION ABU DHABI POLYMERS CO LTD BOROUGE LLC (AE) 2020-07-29 EP disclosed
EP-2650329-B1 Automotive material with high quality perception BOREALIS AG (AT) 2017-04-05 EP disclosed
EP-2906621-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION Abu Dhabi Polymers Co. Ltd (Borouge) LLC. (AE) 2015-08-19 EP disclosed
EP-2410007-B1 Polypropylene/talc composition with improved impact behavior BOREALIS AG (AT) 2014-06-11 EP disclosed
EP-2410008-B1 Bimodal talc filled heterophasic polypropylene BOREALIS AG (AT) 2013-11-20 EP disclosed
EP-2445963-B1 AUTOMOTIVE INTERIOR ARTICLE WITH REDUCED SMELL BOREALIS AG (AT) 2013-10-30 EP disclosed
EP-2445957-B1 POLYPROPYLENE MINERAL COMPOUND WITH REDUCED VOLATILES BOREALIS AG (AT) 2013-10-30 EP disclosed
EP-2650329-A1 Automotive material with high quality perception Borealis AG (AT) 2013-10-16 EP disclosed
EP-2386602-B1 Automotive interior compound BOREALIS AG (AT) 2012-08-29 EP disclosed
EP-2445963-A1 AUTOMOTIVE INTERIOR ARTICLE WITH REDUCED SMELL Borealis AG (AT) 2012-05-02 EP disclosed
EP-2445957-A1 POLYPROPYLENE MINERAL COMPOUND WITH REDUCED VOLATILES Borealis AG (AT) 2012-05-02 EP disclosed
WO-2010149549-A1 AUTOMOTIVE INTERIOR ARTICLE WITH REDUCED SMELL BOREALIS AG (AT) 2010-12-29 WO disclosed
WO-2010149548-A1 POLYPROPYLENE MINERAL COMPOUND WITH REDUCED VOLATILES BOREALIS AG (AT) 2010-12-29 WO disclosed
US-20100286310-A1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2010-11-11 US disclosed
EP-2240542-A1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS Borealis AG (AT) 2010-10-20 EP disclosed
WO-2009092691-A1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2009-07-30 WO disclosed