SCHEMBL2725071

SCHEMBL2725071

CCCC(CCCCCCCCCC1CC(C)(C)NC(C)(C)C1)OC(=O)CC(C(=O)O)C(CC(=O)O)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.31
GMNN O75496 3/20 0.31
LMNA P02545 3/20 0.31
MAPT P10636 3/20 0.31
NPSR1 Q6W5P4 3/20 0.31
CYP1A2 P05177 2/20 0.31
MEN1 O00255 2/20 0.31
HSP90AA1 P07900 2/20 0.31
BLM P54132 2/20 0.31
KMT2A Q03164 2/20 0.31
NR1H4 Q96RI1 2/20 0.31
TP53 P04637 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
HIF1A Q16665 1/20 0.31
GLA P06280 1/20 0.30
PMP22 Q01453 1/20 0.30
CNR1 P21554 1/20 0.30
DAGLA Q9Y4D2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2725429 0.87 GPR84 (0.31) MAPK1GMNNLMNAMAPTNPSR1
SCHEMBL5189226 0.80 NAAA (0.33) TSHR
SCHEMBL4145976 0.78 TDP1 (0.32) TSHR
SCHEMBL2725069 0.78 GPR84 (0.36) MAPK1GMNNLMNAMAPTNPSR1
SCHEMBL373255 0.75 GPR84 (0.32)
SCHEMBL373254 0.74 GPR84 (0.30)
SCHEMBL15321265 0.71 HDAC2 (0.32) TP53TSHR
SCHEMBL15320940 0.71 HDAC2 (0.32) TP53TSHR
SCHEMBL15321034 0.71 HDAC2 (0.32) TP53TSHR
SCHEMBL15321350 0.71 HDAC2 (0.32) TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2906621-B1 HETEROPHASIC POLYPROPYLENE COMPOSITION ABU DHABI POLYMERS CO LTD BOROUGE LLC (AE) 2020-07-29 EP disclosed
EP-2650329-B1 Automotive material with high quality perception BOREALIS AG (AT) 2017-04-05 EP disclosed
EP-2906621-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION Abu Dhabi Polymers Co. Ltd (Borouge) LLC. (AE) 2015-08-19 EP disclosed
EP-2410007-B1 Polypropylene/talc composition with improved impact behavior BOREALIS AG (AT) 2014-06-11 EP disclosed
EP-2410008-B1 Bimodal talc filled heterophasic polypropylene BOREALIS AG (AT) 2013-11-20 EP disclosed
EP-2445957-B1 POLYPROPYLENE MINERAL COMPOUND WITH REDUCED VOLATILES BOREALIS AG (AT) 2013-10-30 EP disclosed
EP-2445963-B1 AUTOMOTIVE INTERIOR ARTICLE WITH REDUCED SMELL BOREALIS AG (AT) 2013-10-30 EP disclosed
EP-2650329-A1 Automotive material with high quality perception Borealis AG (AT) 2013-10-16 EP disclosed
EP-2386602-B1 Automotive interior compound BOREALIS AG (AT) 2012-08-29 EP disclosed
EP-2445957-A1 POLYPROPYLENE MINERAL COMPOUND WITH REDUCED VOLATILES Borealis AG (AT) 2012-05-02 EP disclosed
EP-2445963-A1 AUTOMOTIVE INTERIOR ARTICLE WITH REDUCED SMELL Borealis AG (AT) 2012-05-02 EP disclosed
WO-2012010481-A1 HYBRID FILLER / POLYPROPYLENE COMPOSITE BOREALIS AG (AT) 2012-01-26 WO disclosed
WO-2012010482-A1 POLYPROPYLENE/TALC COMPOSITION WITH IMPROVED IMPACT BEHAVIOR BOREALIS AG (AT) 2012-01-26 WO disclosed
WO-2010149549-A1 AUTOMOTIVE INTERIOR ARTICLE WITH REDUCED SMELL BOREALIS AG (AT) 2010-12-29 WO disclosed
WO-2010149548-A1 POLYPROPYLENE MINERAL COMPOUND WITH REDUCED VOLATILES BOREALIS AG (AT) 2010-12-29 WO disclosed
US-20100286310-A1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2010-11-11 US disclosed
EP-2240542-A1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS Borealis AG (AT) 2010-10-20 EP disclosed
WO-2009092691-A1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2009-07-30 WO disclosed