SCHEMBL2725486

SCHEMBL2725486

CC(C/C(C(=O)O)=C(/CC(C)S(=O)(=O)O)C(=O)O)S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 5/20 0.39
GRIA4 P48058 3/20 0.36
GRIK3 Q13003 3/20 0.36
GRIK5 Q16478 3/20 0.36
GRIA2 P42262 2/20 0.31
GRIK2 Q13002 2/20 0.31
GRIA1 P42261 1/20 0.31
CYP1A2 P05177 1/20 0.31
TP53 P04637 1/20 0.30
SRC P12931 1/20 0.30
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2722763 1.00 GRIK1 (0.39) GRIK1GRIA4GRIK3GRIK5GRIA2
SCHEMBL2722759 1.00 GRIK1 (0.39) GRIK1GRIA4GRIK3GRIK5GRIA2
SCHEMBL11646304 0.85 FNTA (0.34) GRIK1GRIA4GRIK3GRIK5
SCHEMBL11646309 0.85 FNTA (0.34) GRIK1GRIA4GRIK3GRIK5
SCHEMBL27608538 0.81 CA2 (0.32) GRIK1GRIA4GRIK3GRIK5GRIA2
SCHEMBL837488 0.80 SLC22A6 (0.39) CYP1A2GABRPGABRDGABRA1GABRB1
SCHEMBL2722977 0.80 FNTA (0.36) GRIK1GRIA4GRIK3GRIK5
SCHEMBL11646299 0.79
SCHEMBL2472079 0.77 GRIK1 (0.48) GRIK1GRIK2SLC7A5
SCHEMBL27173492 0.76 GRIK1 (0.47) GRIK1GRIK2SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080097029-A1 CONTROLLABLE AND RAPID SOLUBILITY RATE OF WATER-SOLUBLE POLYMERIC FILMS HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2008-04-24 US claimed
US-10113099-B2 High pressure high temperature (HPHT) aqueous drilling mud composition and process for preparing the same ISP INVESTMENTS LLC (US) 2018-10-30 US disclosed
US-10023782-B2 Salt-tolerant, thermally-stable rheology modifiers ISP INVESTMENTS LLC (US) 2018-07-17 US disclosed
US-20170335162-A1 SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS HERCULES LLC 2017-11-23 US disclosed
US-9611416-B2 Salt-tolerant, thermally-stable rheology modifiers ISP INVESTMENTS LLC (US) 2017-04-04 US disclosed
US-20150368538-A1 A NOVEL HIGH PRESSURE HIGH TEMPERATURE (HPHT) AQUEOUS DRILLING MUD COMPOSITION AND PROCESS FOR PREPARING THE SAME ISP INVESTMENTS INC. (US) 2015-12-24 US disclosed
US-20130324443-A1 SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS ISP INVESTMENTS INC. (US) 2013-12-05 US disclosed
WO-2013162902-A1 SYNERGISTIC COMBINATION OF A FLUID LOSS ADDITIVE AND RHEOLOGY MODIFIER ISP INVESTMENTS INC (US) 2013-10-31 WO disclosed
WO-2012061147-A1 SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS ISP INVESTMENTS INC. (US) 2012-05-10 WO disclosed
US-7714064-B2 Controllable and rapid solubility rate of water-soluble polymeric films HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2010-05-11 US disclosed
US-20080097029-A1 CONTROLLABLE AND RAPID SOLUBILITY RATE OF WATER-SOLUBLE POLYMERIC FILMS HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2008-04-24 US disclosed