SCHEMBL837488

SCHEMBL837488

CC(CC(=O)O)S(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
GABRP O00591 2/20 0.37
GABRD O14764 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB1 P18505 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37
GABRA2 P47869 2/20 0.37
GABRB2 P47870 2/20 0.37
GABRA4 P48169 2/20 0.37
GABRE P78334 2/20 0.37
GABRA6 Q16445 2/20 0.37
GABRG1 Q8N1C3 2/20 0.37
GABRG3 Q99928 2/20 0.37
GABRQ Q9UN88 2/20 0.37
CACNA2D1 P54289 2/20 0.37
CACNB3 P54284 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2722759 0.80 GRIK1 (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2725486 0.80 GRIK1 (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL27608538 0.80 CA2 (0.32) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2722763 0.80 GRIK1 (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL23829579 0.79 ALDH1A1 (0.50) TDP1
SCHEMBL5689593 0.79 SLC22A6 (0.39) SLC22A6TDP1GABRPGABRDGABRA1
SCHEMBL7354948 0.79 SLC22A6 (0.39) SLC22A6TDP1GABRPGABRDGABRA1
SCHEMBL17337272 0.77 GABRP (0.41) SLC22A6TDP1GABRPGABRDGABRA1
Sulfuric Acid SCHEMBL75927 0.77 GABRP (0.46) SLC22A6TDP1GABRPGABRDGABRA1
Sulfuric Acid SCHEMBL6854842 0.77 GABRP (0.46) SLC22A6TDP1GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004076400-A1 ANTIMICROBIAL AGENT AGAINST BACTERIA, YEAST AND MOULDS DR. RIEKS GMBH (DE) 2004-09-10 WO claimed
US-20220175808-A1 GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS GLYCOMIMETICS, INC. (US) 2022-06-09 US disclosed
US-11197877-B2 Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists GLYCOMIMETICS. INC. (US) 2021-12-14 US disclosed
US-20200129536-A1 GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS GLYCOMIMETICS, INC. (US) 2020-04-30 US disclosed
US-9482955-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2016-11-01 US disclosed
US-20140329746-A1 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2014-11-06 US disclosed
US-8835654-B2 Method and compositions for treating amyloid-related diseases BHI LIMITED PARTNERSHIP (CA) 2014-09-16 US disclosed
US-20140107027-A1 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES BHI LIMITED PARTNERSHIP (CA) 2014-04-17 US disclosed
US-20140080054-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF FUJIFILM CORPORATION (JP) 2014-03-20 US disclosed
US-8142982-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20120015911-A1 METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES BELLUS HEALTH INC. (CA) 2012-01-19 US disclosed
US-7572459-B2 Prevention infections in humans, animals STARPHARMA PTY LTD. (AU) 2009-08-11 US disclosed
US-20090111049-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-30 US disclosed
WO-2005012210-A2 ANTIMICROBIAL ACTIVE PREPARATIONS CONTAINING TERPENE DERIVATIVES DR. ANDRE RIEKS - LABOR FÜR ENZYMTECHNOLOGIE GMBH (DE) 2005-02-10 WO disclosed
WO-2004076400-A1 ANTIMICROBIAL AGENT AGAINST BACTERIA, YEAST AND MOULDS DR. RIEKS GMBH (DE) 2004-09-10 WO disclosed
WO-1994004555-A1 ANTI-ANDROGENE STEROIDS WITH AN ANNULATED FIVE-MEMBERED RING SCHERING AKTIENGESELLSCHAFT (DE) 1994-03-03 WO disclosed
CN-1041592-A Sultamsulfonamide derivatives and weedicide NISSAN CHEMICAL IND LTD (JP) 1990-04-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220175808-A1 GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS SELE, SELPLG, SELP SLC22A6 929/4885TDP1 3520/4885GABRP 807/4885
US-11197877-B2 Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists SELE, SELPLG, SELP SLC22A6 959/4885TDP1 2966/4885GABRP 1129/4885
US-20140329746-A1 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES APP, PSEN1, PSEN2 SLC22A6 1256/4885TDP1 650/4885GABRP 3088/4885
US-20140107027-A1 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES APP, PSEN1, PSEN2 SLC22A6 1256/4885TDP1 650/4885GABRP 3088/4885
US-20120015911-A1 METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES APP, PSEN1, PSEN2 SLC22A6 1281/4885TDP1 793/4885GABRP 3013/4885
US-20200129536-A1 GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS SELE, SELPLG, SELP SLC22A6 929/4885TDP1 3520/4885GABRP 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.