Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.78 |
| ▸ | PGR | P06401 | 7/20 | 0.78 |
| ▸ | AR | P10275 | 3/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.78 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.78 |
| ▸ | CNR1 | P21554 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.66 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 3/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MLNR | O43193 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008052 | 1.00 | NR3C1 (0.78) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL3999196 | 1.00 | NR3C1 (0.78) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL244665 | 0.92 | NR3C1 (0.66) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL4216341 | 0.92 | NR3C1 (0.66) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL15226045 | 0.92 | NR3C1 (0.66) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL11251406 | 0.91 | NR3C1 (0.72) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL15225970 | 0.91 | NR3C1 (0.64) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL11081794 | 0.90 | NR3C1 (0.68) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL4218105 | 0.90 | NR3C1 (0.63) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL4102916 | 0.89 | NR3C1 (0.72) | NR3C1PGRARPTGS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578169-B1 | PHARMACEUTICAL FORMULATIONS COMPRISING 4-{(1 R)-2-[(6-{2-[(2,6-DICHLOROBENZYL)OXY]ETHOXY}HEXYL)AMINO]-1-HYDROXYETHYL}-2-(HYDROXYMETHYL)PHENOL | GLAXO GROUP LTD (GB) | 2024-06-26 | — | — | EP | disclosed |