SCHEMBL27255285

SCHEMBL27255285

c1ccc(-c2ccc(-c3cc(-c4ccccc4)nc(-c4ccc(-c5ccc(-c6ccc7oc8cc9ccccc9cc8c7c6)cc5)c5ccccc45)n3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
MAPK1 P28482 3/20 0.40
PLA2G2A P14555 3/20 0.39
PLA2G4A P47712 3/20 0.39
ACACA Q13085 3/20 0.39
HSD17B10 Q99714 3/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
ALDH1A1 P00352 4/20 0.37
MAPT P10636 4/20 0.37
HPGD P15428 4/20 0.37
KDM4E B2RXH2 3/20 0.37
TSHR P16473 2/20 0.37
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27254960 0.96 KMT2A (0.40) KMT2AMAPK1PLA2G2APLA2G4AACACA
SCHEMBL27255282 0.91 PLA2G2A (0.44) KMT2AMAPK1PLA2G2APLA2G4AACACA
SCHEMBL27256508 0.91 PLA2G2A (0.44) KMT2AMAPK1PLA2G2APLA2G4AACACA
SCHEMBL27255281 0.90 KMT2A (0.38) KMT2AMAPK1PLA2G2APLA2G4AACACA
SCHEMBL27255451 0.89 ALOX5 (0.39) KMT2AMAPK1PLA2G2APLA2G4AACACA
SCHEMBL27391952 0.88 KMT2A (0.40) KMT2AMAPK1PLA2G2APLA2G4AACACA
SCHEMBL27255289 0.86 PLA2G2A (0.43) KMT2AMAPK1PLA2G2APLA2G4AHSD17B10
SCHEMBL26750782 0.85 KDM4E (0.41) KMT2AMAPK1PLA2G2APLA2G4AHSD17B10
SCHEMBL23633701 0.85 KDM4E (0.37) KMT2AMAPK1PLA2G2APLA2G4AHSD17B10
SCHEMBL15501273 0.84 KMT2A (0.43) KMT2AMAPK1PLA2G2APLA2G4AACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024024726-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2024-02-01 WO disclosed