SCHEMBL27256289

SCHEMBL27256289

Cc1cc(Br)cc(C(N)=O)c1NC(=O)c1cc(Br)nn1CC(F)F

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ TAS1R3 Q7RTX0 1/20 0.32
▸ TAS1R1 Q7RTX1 1/20 0.32
▸ TAS1R2 Q8TE23 1/20 0.32
▸ ALDH1A1 P00352 4/20 0.32
▸ HPGD P15428 1/20 0.32
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ SLC2A1 P11166 2/20 0.31
▸ SLC2A3 P11169 2/20 0.31
▸ SLC2A4 P14672 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27257568 0.91 LMNA (0.34) LMNAMAPTTAS1R3TAS1R1TAS1R2
SCHEMBL27256242 0.90 LMNA (0.33) LMNAMAPTALDH1A1HPGDMEN1
SCHEMBL27257490 0.90 LMNA (0.37) LMNAMAPTTAS1R3TAS1R1TAS1R2
SCHEMBL30961156 0.90 LMNA (0.34) LMNAMAPTTAS1R3TAS1R1TAS1R2
SCHEMBL27256308 0.90 LMNA (0.34) LMNAMAPTTAS1R3TAS1R1TAS1R2
SCHEMBL27257376 0.88 AURKA (0.38) LMNAMAPTALDH1A1SLC2A1SLC2A3
SCHEMBL30961129 0.88 AURKA (0.38) LMNAMAPTALDH1A1SLC2A1SLC2A3
SCHEMBL30961206 0.87 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4
SCHEMBL27256852 0.87 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4
SCHEMBL27257518 0.86 MAPT (0.33) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133426-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS AND COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 — — WO disclosed
WO-2024133426-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS AND COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 — — WO disclosed
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