SCHEMBL27257518

SCHEMBL27257518

Cc1cc(Br)cc(C(N)=O)c1NC(=O)c1cc(OCC(F)F)nn1CC(F)F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.33
▸ LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27257509 0.90 SLC2A1 (0.32) MAPTLMNA
SCHEMBL30961104 0.86 SLC2A1 (0.35) —
SCHEMBL27256289 0.86 LMNA (0.34) MAPTLMNA
SCHEMBL27257568 0.85 LMNA (0.34) MAPTLMNA
SCHEMBL27257497 0.85 MAPT (0.31) MAPT
SCHEMBL27257490 0.85 LMNA (0.37) MAPTLMNA
SCHEMBL27257650 0.83 BACE1 (0.30) —
SCHEMBL30961168 0.83 BACE1 (0.30) —
SCHEMBL30961129 0.83 AURKA (0.38) MAPTLMNA
SCHEMBL27257376 0.83 AURKA (0.38) MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133426-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS AND COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 — — WO disclosed
WO-2024133426-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS AND COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 — — WO disclosed
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