SCHEMBL27257477

SCHEMBL27257477

Cc1cc(Br)cc2c(=O)oc(-c3cc(Cl)nn3C3CC3)nc12

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 1/20 0.34
▸ RXFP1 Q9HBX9 2/20 0.33
▸ DHODH Q02127 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27256328 0.89 RAB9A (0.35) RAB9ARXFP1KMT2A
SCHEMBL30961143 0.89 RAB9A (0.35) RAB9ARXFP1KMT2A
SCHEMBL27257407 0.85 RAB9A (0.34) RAB9ARXFP1
SCHEMBL27256211 0.83 PDE10A (0.35) —
SCHEMBL27256388 0.77 PDE10A (0.34) —
SCHEMBL30961199 0.77 PDE10A (0.34) —
SCHEMBL30961134 0.76 PDE10A (0.34) —
SCHEMBL27256457 0.76 PDE10A (0.34) —
SCHEMBL30961109 0.76 PDE4A (0.30) —
SCHEMBL27256455 0.76 PDE10A (0.36) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133426-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS AND COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 — — WO disclosed
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