Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30788892 | 0.85 | SLC6A9 (0.37) | EPHX2SLC1A5KIF11 | |
| SCHEMBL32670641 | 0.85 | SLC6A9 (0.37) | EPHX2SLC1A5KIF11 | |
| SCHEMBL27257486 | 0.85 | SLC6A9 (0.37) | EPHX2SLC1A5KIF11 | |
| SCHEMBL27257479 | 0.85 | SLC6A9 (0.37) | EPHX2SLC1A5KIF11 | |
| SCHEMBL27259706 | 0.85 | SLC6A9 (0.38) | EPHX2SLC1A5KIF11 | |
| SCHEMBL6984588 | 0.76 | HSD11B1 (0.44) | EPHX2 | |
| SCHEMBL1261305 | 0.74 | DPP4 (0.46) | POLBKMT2ATDP1KIF11 | |
| SCHEMBL32670418 | 0.72 | GRIN1 (0.41) | EPHX2 | |
| SCHEMBL28102643 | 0.70 | HRH1 (0.55) | POLBKMT2ATDP1NOS1SLC1A5 | |
| SCHEMBL28102642 | 0.70 | HRH1 (0.55) | POLBKMT2ATDP1NOS1SLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030960-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2024-02-08 | — | — | WO | disclosed |