SCHEMBL272575

SCHEMBL272575

CSc1ccncc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10872946 0.97
Iodide SCHEMBL11058783 0.97
Phosphonic Acid SCHEMBL9636974 0.85 KMT2A (0.44)
Biphenyl SCHEMBL27988240 0.85 NOTUM (0.61)
SCHEMBL30518879 0.84 MAPT (0.55)
SCHEMBL9636978 0.78 KMT2A (0.38)
Methylphenylsulfide SCHEMBL27402679 0.78 TSHR (0.45)
SCHEMBL8361629 0.78 LOXL2 (0.46)
SCHEMBL11485483 0.78 SLC6A4 (0.51)
SCHEMBL14022350 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117003787-A Selective silicon-based-arylation method of olefin compound 南京大学 2023-11-07 CN claimed
WO-2003106454-A1 1H-ISOQUINOLINE-OXAZOLIDINONE DERIVATIES AND THEIR USE AS ANTIBACTERIAL AGENTS ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) 2003-12-24 WO claimed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP claimed
EP-0761672-B1 Cephalosporins containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments AVENTIS PHARMA SA (FR) 2001-11-07 EP claimed
EP-0551034-B1 Antibiotic cephalosporins having in position 7 a substituted benzyloxyimino radical HOECHST MARION ROUSSEL INC (FR) 2000-09-20 EP claimed
CN-1178671-A Method for preparing novel cephalosporin medicine composition containing substituted benzyloxy imino on the 7 th position ROUSSEL UCLAF CO (FR) 1998-04-15 CN claimed
US-5710147-A ANTIBIOTICS ROUSSEL UCLAF (FR) 1998-01-20 US claimed
EP-0761672-A1 Cephalosporin containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments ROUSSEL UCLAF (FR) 1997-03-12 EP claimed
US-5494666-A BETA-LACTAMASE INHIBITORS, ANTIBACTERIALS HOFFMANN-LA ROCHE INC. (US) 1996-02-27 US claimed
EP-0693496-A1 Novel cephalosporins having a substituted benzyloxyimino radical in position 7, process for their preparation and their use as medicaments ROUSSEL UCLAF (FR) 1996-01-24 EP claimed
US-5464617-A 1H-2,6a-diazacyclobut(cd)indene-6-carboxylic acid derivatives, antibiotics HOFFMANN-LA ROCHE INC. (US) 1995-11-07 US claimed
US-5455238-A Bactericides ROUSSEL UCLAF (FR) 1995-10-03 US claimed
EP-0628562-A1 Cephalospornis having in position 7 as substituted axymino radical, intermediates, processes for their preparation and their use as medicaments ROUSSEL UCLAF (FR) 1994-12-14 EP claimed
EP-0551034-A2 Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments ROUSSEL UCLAF (FR) 1993-07-14 EP claimed
EP-0230068-B1 USE OF A GEMINAL DIPHOSPHONIC ACID COMPOUND TO PREPARE A MEDICAMENT Norwich Eaton Pharmaceuticals, Inc. (US) 1992-07-15 EP claimed
US-4839352-A ANTIBIOTICS MERCK & CO., INC. (US) 1989-06-13 US claimed
EP-0234516-A1 1,6-Naphthyridine derivatives, process for their preparation and medicine containing them for the treatment of vascular diseases GÖDECKE AKTIENGESELLSCHAFT (DE) 1987-09-02 EP claimed
EP-0175363-A2 4,5-Dihydro-3(2H)-pyridazinones, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1986-03-26 EP claimed
EP-0113245-A2 Cephalosporin derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-07-11 EP claimed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US claimed