Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 5/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636978 | 0.88 | KMT2A (0.38) | KMT2ANOS1MEN1DDAH1SMN1; SMN2 | |
| SCHEMBL272575 | 0.85 | — | — | |
| Phosphonic Acid SCHEMBL7177636 | 0.83 | ALDH1A1 (0.50) | NOS1ALDH1A1PLK1NOS3 | |
| Iodide SCHEMBL11058783 | 0.83 | — | — | |
| SCHEMBL10872946 | 0.83 | — | — | |
| Phosphonic Acid SCHEMBL9637901 | 0.75 | MEN1 (0.41) | KMT2AMEN1SMN1; SMN2ALDH1A1CYP1A2 | |
| Phosphonic Acid SCHEMBL31291502 | 0.74 | ALDH1A1 (0.43) | KMT2ANOS1MEN1SMN1; SMN2ALDH1A1 | |
| Biphenyl SCHEMBL27988240 | 0.73 | NOTUM (0.61) | KMT2ANOS1MEN1DDAH1SMN1; SMN2 | |
| SCHEMBL30518879 | 0.71 | MAPT (0.55) | NOS1DDAH1SMN1; SMN2GCGRMAPK14 | |
| Phosphonic Acid SCHEMBL8588139 | 0.70 | SLC6A4 (0.41) | ALDH1A1PLK1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230068-B1 | USE OF A GEMINAL DIPHOSPHONIC ACID COMPOUND TO PREPARE A MEDICAMENT | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-07-15 | — | — | EP | claimed |
| US-4902679-A | TREATING BONE DISORDERS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-02-20 | — | — | US | claimed |
| EP-0230068-A2 | Use of a geminal diphosphonic acid compound to prepare a medicament | Norwich Eaton Pharmaceuticals, Inc. (US) | 1987-07-29 | — | — | EP | claimed |
| EP-0230068-B1 | USE OF A GEMINAL DIPHOSPHONIC ACID COMPOUND TO PREPARE A MEDICAMENT | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-07-15 | — | — | EP | disclosed |
| US-4902679-A | TREATING BONE DISORDERS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0230068-A2 | Use of a geminal diphosphonic acid compound to prepare a medicament | Norwich Eaton Pharmaceuticals, Inc. (US) | 1987-07-29 | — | — | EP | disclosed |