Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LONP1 | P36776 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973738 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2ATMCYP2D6 | |
| SCHEMBL27257536 | 0.79 | KDM4E (0.35) | KDM4EALDH1A1SMN1; SMN2PSMB5ATM | |
| SCHEMBL1579715 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2ATMRAB9A | |
| SCHEMBL5706462 | 0.74 | KDM4E (0.34) | KDM4EALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL10714528 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2ATMPOLB | |
| SCHEMBL8508786 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2PSMB5CYP2D6 | |
| SCHEMBL6847249 | 0.72 | KDM4E (0.40) | KDM4EHPGD | |
| SCHEMBL25227677 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7117628 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2CYP19A1POLB | |
| SCHEMBL2861698 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618974-A1 | OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |