Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257535 | 0.79 | KDM4E (0.37) | KDM4EATMPSMB5ALDH1A1HPGD | |
| SCHEMBL27602442 | 0.77 | CYP2D6 (0.38) | KDM4EALDH1A1HPGDCYP2D6CYP19A1 | |
| SCHEMBL7995340 | 0.69 | — | — | |
| SCHEMBL1560979 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL28024462 | 0.67 | KDM4E (0.36) | KDM4EATMALDH1A1CYP2D6HPGDS | |
| SCHEMBL27256888 | 0.67 | — | — | |
| SCHEMBL28235833 | 0.66 | ALDH1A1 (0.35) | KDM4EATMALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL27772497 | 0.66 | ATM (0.40) | KDM4EATMALDH1A1CYP2D6HPGDS | |
| SCHEMBL20873143 | 0.66 | ALDH1A1 (0.44) | PSMB5ALDH1A1HPGDCYP2D6CYP2C9 | |
| SCHEMBL19003627 | 0.64 | POLB (0.35) | KDM4EATMALDH1A1CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |