Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LONP1 | P36776 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 2/20 | 0.32 |
| ▸ | BTD | P43251 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1579715 | 0.84 | KDM4E (0.42) | KDM4ESMN1; SMN2ALDH1A1LONP1CYP2D6 | |
| SCHEMBL27257535 | 0.80 | KDM4E (0.37) | KDM4ESMN1; SMN2ALDH1A1LONP1CYP2D6 | |
| SCHEMBL19003627 | 0.80 | POLB (0.35) | KDM4ESMN1; SMN2ALDH1A1LONP1CYP2D6 | |
| SCHEMBL18595067 | 0.78 | SMN1; SMN2 (0.37) | KDM4ESMN1; SMN2ALDH1A1LONP1CYP2D6 | |
| SCHEMBL5706462 | 0.78 | KDM4E (0.34) | KDM4ESMN1; SMN2ALDH1A1CYP19A1 | |
| SCHEMBL10714528 | 0.78 | KDM4E (0.39) | KDM4ESMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL25225144 | 0.78 | KDM4E (0.41) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL10701796 | 0.77 | KDM4E (0.31) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL18881769 | 0.77 | ATM (0.34) | KDM4ESMN1; SMN2ALDH1A1LONP1CYP2D6 | |
| SCHEMBL5159765 | 0.77 | CYP2D6 (0.33) | KDM4ESMN1; SMN2ALDH1A1LONP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101830661-B | Additive for warm-mixing rubber-asphalt mixture and mixing method of mixture | RES INST HIGHWAY MINI TRANSP | 2012-08-29 | — | — | CN | disclosed |
| CN-101830661-A | Additive for warm-mixing rubber-asphalt mixture and mixing method of mixture | RES INST HIGHWAY MINI TRANSP | 2010-09-15 | — | — | CN | disclosed |
| US-6288066-B1 | ANTIDIABETIC AGENTS; OXIDATION, HYDROLYSIS | AVENTIS PHARMA S.A. (FR) | 2001-09-11 | — | — | US | disclosed |