Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257576 | 0.82 | LMNA (0.34) | LMNA | |
| SCHEMBL27256669 | 0.79 | — | — | |
| SCHEMBL27257067 | 0.76 | GRIN1 (0.32) | — | |
| SCHEMBL27257010 | 0.74 | — | — | |
| SCHEMBL27257504 | 0.74 | — | — | |
| SCHEMBL27257251 | 0.73 | — | — | |
| SCHEMBL27257215 | 0.72 | — | — | |
| SCHEMBL30967145 | 0.70 | HCRTR2 (0.34) | — | |
| SCHEMBL27256726 | 0.70 | KDM4E (0.30) | — | |
| SCHEMBL27255630 | 0.70 | HCRTR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |