Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257575 | 0.84 | ALDH1A1 (0.34) | — | |
| SCHEMBL30967052 | 0.84 | ALDH1A1 (0.34) | — | |
| SCHEMBL27257578 | 0.82 | LMNA (0.34) | LMNA | |
| SCHEMBL27256666 | 0.79 | GRIN1 (0.32) | GRIN1GRIN2B | |
| SCHEMBL27257065 | 0.76 | GRIN1 (0.36) | GRIN1GRIN2B | |
| SCHEMBL30967138 | 0.73 | GRIN1 (0.32) | GRIN1GRIN2B | |
| SCHEMBL30967123 | 0.73 | GAA (0.31) | GRIN1GRIN2B | |
| SCHEMBL27257009 | 0.73 | GAA (0.31) | GRIN1GRIN2B | |
| SCHEMBL27257503 | 0.73 | GRIN1 (0.32) | GRIN1GRIN2B | |
| SCHEMBL27257249 | 0.73 | GRIN1 (0.32) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618974-A1 | OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |