Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | KYNU | Q16719 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27254861 | 1.00 | PMP22 (0.40) | PMP22DPP4KIF11LMNASMN1; SMN2 | |
| SCHEMBL27257475 | 0.88 | SLC6A4 (0.39) | PMP22CYP2C19 | |
| SCHEMBL32670641 | 0.84 | SLC6A9 (0.37) | PMP22KIF11 | |
| SCHEMBL30788892 | 0.84 | SLC6A9 (0.37) | PMP22KIF11 | |
| SCHEMBL27257486 | 0.84 | SLC6A9 (0.37) | PMP22KIF11 | |
| SCHEMBL27257479 | 0.84 | SLC6A9 (0.37) | PMP22KIF11 | |
| SCHEMBL27270182 | 0.81 | PMP22 (0.33) | PMP22 | |
| SCHEMBL1261305 | 0.80 | DPP4 (0.46) | DPP4KIF11LMNASMN1; SMN2NPSR1 | |
| SCHEMBL27255244 | 0.78 | LTA4H (0.43) | PMP22 | |
| SCHEMBL25241533 | 0.77 | PMP22 (0.47) | PMP22KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030960-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2024-02-08 | — | — | WO | disclosed |