Toluene

Toluene

SCHEMBL27258338

Cc1cccc(C)c1C.Cc1ccccc1.c1ccccc1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.65
TSHR P16473 3/20 0.65
LMNA P02545 2/20 0.65
ALOX12 P18054 1/20 0.65
TRPA1 O75762 2/20 0.48
ATM Q13315 1/20 0.48
NPSR1 Q6W5P4 1/20 0.46
HPGD P15428 1/20 0.46
RAPGEF4 Q8WZA2 1/20 0.45
CYP1A2 P05177 3/20 0.44
MEN1 O00255 1/20 0.44
AKR1B10 O60218 1/20 0.44
ABCB11 O95342 1/20 0.44
DHFR P00374 1/20 0.44
MPO P05164 1/20 0.44
CYP3A4 P08684 1/20 0.44
CHRM1 P11229 1/20 0.44
CYP2C9 P11712 1/20 0.44
AKR1B1 P15121 1/20 0.44
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL337110 1.00 ACHE (0.65) ACHETSHRLMNAALOX12TRPA1
P-Xylene SCHEMBL1959829 0.88 ACHE (0.53) ACHETSHRLMNAALOX12TRPA1
Benzene SCHEMBL22829865 0.87 TRPA1 (0.58) ACHETSHRLMNAALOX12TRPA1
O-Xylene SCHEMBL8979417 0.86 ACHE (0.61) ACHETSHRLMNAALOX12TRPA1
Toluene SCHEMBL5573198 0.85 ACHE (0.69) ACHETSHRLMNAALOX12TRPA1
O-Xylene SCHEMBL11240856 0.84 ACHE (0.79) ACHETSHRLMNAALOX12NPSR1
O-Xylene SCHEMBL8910096 0.84 ACHE (0.79) ACHETSHRLMNAALOX12NPSR1
O-Xylene SCHEMBL10822510 0.84 ACHE (0.79) ACHETSHRLMNAALOX12NPSR1
SCHEMBL20960205 0.84 ACHE (0.71) ACHETSHRLMNAALOX12TRPA1
O-Xylene SCHEMBL1088985 0.84 ACHE (0.79) ACHETSHRLMNAALOX12NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1026316-C Low-carbon hydrocarbon aromatization process FUSHUN PETORLEUM COLLAGE (CN) 1994-10-26 CN disclosed