Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2348815 | 0.81 | ERAP1 (0.47) | ANPEPERAP1ERAP2ACEALDH1A1 | |
| SCHEMBL5744615 | 0.74 | ACP3 (0.49) | ACP3ANPEPERAP1ERAP2ACE | |
| SCHEMBL9074900 | 0.74 | CYP2D6 (0.43) | EPHX1CYP1A2MAPK1CYP2C19LMNA | |
| SCHEMBL18795090 | 0.72 | CYP2D6 (0.41) | EPHX1CYP1A2MAPK1CYP2C19LMNA | |
| SCHEMBL27592490 | 0.71 | EPHX1 (0.68) | ACP3EPHX1ANPEPERAP1ERAP2 | |
| SCHEMBL8465661 | 0.71 | ACP3 (0.44) | ACP3ANPEPERAP1ERAP2ALDH1A1 | |
| SCHEMBL27833870 | 0.71 | ACP3 (0.44) | ACP3ANPEPERAP1ERAP2ALDH1A1 | |
| SCHEMBL27640130 | 0.70 | ACP3 (0.45) | ACP3ANPEPERAP1ERAP2CYP3A4 | |
| SCHEMBL5814047 | 0.70 | SLC15A1 (0.53) | EPHX1ANPEPCYP1A2SLC15A1 | |
| SCHEMBL28328434 | 0.70 | ACP3 (0.45) | ACP3ANPEPERAP1ERAP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1025497-C | Improved method for preparing 3- (4-chlorphenyl) -3- (3, 4-dimethoxyphenyl) acryloyl morpholine | SHELL INT RESEARCH (NL) | 1994-07-20 | — | — | CN | disclosed |
| CN-1037899-A | Preparation 3, the improving one's methods of 3-diphenylprop acrylamide | SHELL INT RESEARCH (NL) | 1989-12-13 | — | — | CN | disclosed |
| CN-1037899-A | Preparation 3, the improving one's methods of 3-diphenylprop acrylamide | SHELL INT RESEARCH (NL) | 1989-12-13 | — | — | CN | disclosed |