Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416141 | 0.88 | SLC15A1 (0.55) | ERAP1ANPEPERAP2SLC15A1METAP2 | |
| SCHEMBL7416145 | 0.88 | SLC15A1 (0.55) | ERAP1ANPEPERAP2SLC15A1METAP2 | |
| SCHEMBL7416137 | 0.88 | SLC15A1 (0.55) | ERAP1ANPEPERAP2SLC15A1METAP2 | |
| SCHEMBL3131714 | 0.88 | SLC15A1 (0.55) | ERAP1ANPEPERAP2SLC15A1METAP2 | |
| Hydrochloric Acid SCHEMBL7363142 | 0.87 | SLC15A1 (0.54) | ERAP1ANPEPERAP2SLC15A1METAP2 | |
| Hydrochloric Acid SCHEMBL7363138 | 0.87 | SLC15A1 (0.54) | ERAP1ANPEPERAP2SLC15A1METAP2 | |
| Hydrochloric Acid SCHEMBL7363137 | 0.87 | SLC15A1 (0.54) | ERAP1ANPEPERAP2SLC15A1METAP2 | |
| SCHEMBL5814047 | 0.83 | SLC15A1 (0.53) | ANPEPSLC15A1CYP1A2ALPIPKM | |
| SCHEMBL10217512 | 0.81 | CTSL (0.51) | ERAP1ANPEPERAP2METAP2METAP1 | |
| SCHEMBL27258989 | 0.81 | ACP3 (0.44) | ERAP1ANPEPERAP2SLC15A1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358663-A1 | ENANTIOSELECTIVE SYNTHESIS OF -AMINO- , -UNSATURATED CARBOXYLIC ACID DERIVATIVES | Novartis AG (CH) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010055162-A1 | ENANTIOSELECTIVE SYNTHESIS OF γ-AMINO-α,β-UNSATURATED CARBOXYLIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2010-05-20 | — | — | WO | disclosed |