Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.47 |
| ▸ | HTR3B | O95264 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941460 | 0.91 | HTR3E (0.54) | GSTP1CA1CA2CA9HTR3E | |
| SCHEMBL27259386 | 0.90 | ESR1 (0.52) | GSTP1ESR1ESR2CYP17A1CYP19A1 | |
| SCHEMBL28165444 | 0.85 | MEN1 (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27251963 | 0.82 | ESR1 (0.44) | GSTP1ESR1ESR2ALOX5CA1 | |
| SCHEMBL30239998 | 0.79 | ESR1 (0.71) | GSTP1ESR1ESR2CYP17A1CYP19A1 | |
| SCHEMBL5013872 | 0.79 | ESR1 (0.71) | GSTP1ESR1ESR2CYP17A1CYP19A1 | |
| SCHEMBL15902840 | 0.79 | ESR1 (0.71) | GSTP1ESR1ESR2CYP17A1CYP19A1 | |
| SCHEMBL30239993 | 0.79 | ESR1 (0.71) | GSTP1ESR1ESR2CYP17A1CYP19A1 | |
| SCHEMBL239121 | 0.79 | ESR1 (0.71) | GSTP1ESR1ESR2CYP17A1CYP19A1 | |
| SCHEMBL30603836 | 0.79 | ESR1 (0.71) | GSTP1ESR1ESR2CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024526-B2 | Fused polycyclic aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024526-B2 | Fused polycyclic aromatic compound | AHR, PAH, H1-2 | GSTP1 3549/4885ESR1 645/4885ESR2 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.