Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27259593 | 0.90 | GSTP1 (0.50) | ESR1ESR2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL27251963 | 0.85 | ESR1 (0.44) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL27251961 | 0.81 | ESR1 (0.41) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL941460 | 0.81 | HTR3E (0.54) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL464532 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL30304006 | 0.80 | ESR1 (0.73) | ESR1ESR2PGRCYP11B1CYP11B2 | |
| SCHEMBL16107069 | 0.80 | ESR1 (0.73) | ESR1ESR2PGRCYP11B1CYP11B2 | |
| SCHEMBL13179896 | 0.79 | MAOA (0.44) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL28165444 | 0.79 | MEN1 (0.47) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL27251882 | 0.76 | CYP1A2 (0.41) | ESR1ESR2ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024526-B2 | Fused polycyclic aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024526-B2 | Fused polycyclic aromatic compound | AHR, PAH, H1-2 | ESR1 645/4885ESR2 255/4885PGR 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.