Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209012 | 0.84 | CYP3A4 (1.00) | CYP3A4ALDH1A1CYP2C9CYP2C19RECQL | |
| SCHEMBL27914028 | 0.81 | CYP3A4 (0.72) | CYP3A4ALDH1A1CYP2C9CYP2C19RECQL | |
| SCHEMBL17911429 | 0.81 | CYP3A4 (0.72) | CYP3A4ALDH1A1CYP2C9CYP2C19RECQL | |
| SCHEMBL25390399 | 0.75 | ALDH1A1 (0.63) | CYP3A4ALDH1A1CYP2C9CYP2C19RECQL | |
| SCHEMBL25390401 | 0.75 | ALDH1A1 (0.63) | CYP3A4ALDH1A1CYP2C9CYP2C19RECQL | |
| SCHEMBL21073983 | 0.75 | CYP3A4 (0.62) | CYP3A4ALDH1A1CYP2C9CYP2C19RECQL | |
| SCHEMBL8497636 | 0.75 | ALDH1A1 (0.62) | CYP3A4ALDH1A1CYP2C9CYP2C19RECQL | |
| SCHEMBL30780840 | 0.74 | ALDH1A1 (0.61) | CYP3A4ALDH1A1CYP2C9CYP2C19TGM2 | |
| SCHEMBL10594826 | 0.72 | CYP2C19 (0.59) | CYP3A4ALDH1A1CYP2C9CYP2C19RECQL | |
| SCHEMBL30758297 | 0.72 | CYP2C19 (0.59) | CYP3A4ALDH1A1CYP2C9CYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013162902-A1 | SYNERGISTIC COMBINATION OF A FLUID LOSS ADDITIVE AND RHEOLOGY MODIFIER | ISP INVESTMENTS INC (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013138156-A1 | SYNTHESIS AND APPLICATION OF HIGH PRESSURE HIGH TEMPERATURE FLUID LOSS ADDITIVE AND RHEOLOGY STABILIZER | ISP INVESTMENTS INC. (US) | 2013-09-19 | — | — | WO | disclosed |
| WO-2012061147-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2012-05-10 | — | — | WO | disclosed |