SCHEMBL7209012

SCHEMBL7209012

C=CC(=O)NC(C)(C)Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 1.00
ALDH1A1 P00352 2/20 1.00
CYP2C9 P11712 1/20 1.00
CYP2C19 P33261 1/20 1.00
LMNA P02545 1/20 0.50
CYP2D6 P10635 1/20 0.50
OPRM1 P35372 2/20 0.47
OPRD1 P41143 2/20 0.47
OPRK1 P41145 2/20 0.47
TGM2 P21980 2/20 0.44
RECQL P46063 2/20 0.44
CYP1A2 P05177 1/20 0.44
MAPK1 P28482 1/20 0.43
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
MMP8 P22894 4/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17911429 0.84 CYP3A4 (0.72) CYP3A4ALDH1A1CYP2C9CYP2C19LMNA
SCHEMBL27914028 0.84 CYP3A4 (0.72) CYP3A4ALDH1A1CYP2C9CYP2C19LMNA
SCHEMBL2725968 0.84 CYP3A4 (0.72) CYP3A4ALDH1A1CYP2C9CYP2C19LMNA
SCHEMBL7873834 0.84 CYP3A4 (0.72) CYP3A4ALDH1A1CYP2C9CYP2C19LMNA
SCHEMBL20763320 0.83 ALDH1A1 (0.70) CYP3A4ALDH1A1CYP2C9CYP2C19LMNA
SCHEMBL5948337 0.80 CYP3A4 (0.67) CYP3A4ALDH1A1CYP2C9CYP2C19LMNA
SCHEMBL20763052 0.80 ALDH1A1 (0.67) CYP3A4ALDH1A1CYP2C9CYP2C19OPRM1
SCHEMBL6514301 0.79 ALDH1A1 (0.65) CYP3A4ALDH1A1CYP2C9CYP2C19LMNA
SCHEMBL20763189 0.78 ALDH1A1 (0.63) CYP3A4ALDH1A1CYP2C9CYP2C19OPRM1
SCHEMBL20763322 0.78 ALDH1A1 (0.63) CYP3A4ALDH1A1CYP2C9CYP2C19TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12070531-B2 Polymeric coatings COLOPLAST A/S (DK) 2024-08-27 US disclosed
EP-3668555-B2 POLYMERIC COATINGS COLOPLAST AS (DK) 2024-07-24 EP disclosed
US-11685708-B2 Acrylamide photoinitiators COLOPLAST A/S (DK) 2023-06-27 US disclosed
US-11685708-B2 Acrylamide photoinitiators COLOPLAST A/S (DK) 2023-06-27 US disclosed
US-11685708-B2 Acrylamide photoinitiators COLOPLAST A/S (DK) 2023-06-27 US disclosed
CN-110352186-B Acrylamide photoinitiator 科洛普拉斯特公司 2022-10-04 CN disclosed
US-20220145116-A1 AQUEOUS COATING COMPOSITION ALLNEX NETHERLANDS (NL) 2022-05-12 US disclosed
EP-3601213-B1 ACRYLAMIDE PHOTOINITIATORS COLOPLAST AS (DK) 2022-05-11 EP disclosed
EP-3601213-B1 ACRYLAMIDE PHOTOINITIATORS COLOPLAST AS (DK) 2022-05-11 EP disclosed
CN-111032102-B Polymer coatings 科洛普拉斯特公司 2022-03-22 CN disclosed
CN-111032102-A Polymer coatings 科洛普拉斯特公司 2020-04-17 CN disclosed
US-20200109106-A1 ACRYLAMIDE PHOTOINITIATORS COLOPLAST A/S (DK) 2020-04-09 US disclosed
WO-2019034222-A1 POLYMERIC COATINGS COLOPLAST A/S (DK) 2019-02-21 WO disclosed
US-8927094-B2 Printed article and method of manufacturing printed article SEIKO EPSON CORPORATION (JP) 2015-01-06 US disclosed
US-20120237735-A1 PRINTED ARTICLE AND METHOD OF MANUFACTURING PRINTED ARTICLE SEIKO EPSON CORPORATION (JP) 2012-09-20 US disclosed
US-20120237738-A1 PRINTED ARTICLE AND METHOD OF MANUFACTURING PRINTED ARTICLE SEIKO EPSON CORPORATION (JP) 2012-09-20 US disclosed
US-6617389-B1 Terpolymers of an unsaturated carboxylic acid, another unsaturated monomer and a nitrogenous adhesion promoting, copolymerizable monomer;high gloss topcoats AKZO NOBEL N.V. (NL) 2003-09-09 US disclosed
EP-0927198-B1 AQUEOUS POLYMER DISPERSION FOR USE IN WATER BASED GLOSSY LACQUERS AKZO NOBEL NV (NL) 2001-05-23 EP disclosed
EP-0927198-A1 AQUEOUS POLYMER DISPERSION FOR USE IN WATER BASED GLOSSY LACQUERS Akzo Nobel N.V. (NL) 1999-07-07 EP disclosed
WO-1998012230-A1 AQUEOUS POLYMER DISPERSION FOR USE IN WATER BASED GLOSSY LACQUERS AKZO NOBEL N.V. (NL) 1998-03-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685708-B2 Acrylamide photoinitiators AAAS, ACR, CRYAA CYP3A4 308/4885ALDH1A1 368/4885CYP2C9 234/4885
US-20200109106-A1 ACRYLAMIDE PHOTOINITIATORS AAAS, ACR, CRYAA CYP3A4 308/4885ALDH1A1 368/4885CYP2C9 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.