SCHEMBL27262005

SCHEMBL27262005

C[C@H](N)C(=O)c1cc[c]cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.33
PGR P06401 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
HTR2A P28223 1/20 0.32
HRH1 P35367 1/20 0.32
KCNH2 Q12809 1/20 0.32
KDM4E B2RXH2 1/20 0.31
DBH P09172 1/20 0.31
GAA P10253 1/20 0.31
RECQL P46063 1/20 0.31
LMNA P02545 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
GSK3B P49841 1/20 0.31
PARP10 Q53GL7 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.30
ESR2 Q92731 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27338904 1.00 ELANE (0.33) ELANEPGRADRA2AADRA2BHTR2A
SCHEMBL17201709 0.83 SPHK1 (0.32) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL27601754 0.83 SLC7A5 (0.38) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL4316411 0.82 KDM4E (0.47) ELANEPGRADRA2AADRA2BHTR2A
SCHEMBL27643168 0.80 LMNA (0.34) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL27707450 0.79 SLC7A5 (0.44) ELANESLC6A2SLC6A4SLC6A3
SCHEMBL28131090 0.78 KMT2A (0.36) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL27749830 0.78 HDAC3 (0.37) PGRADRA2AADRA2BHTR2AHRH1
Dealkylated Diethylpropion SCHEMBL25176894 0.77 TDP1 (0.52) ELANEPGRADRA2AADRA2BHTR2A
Cathinone SCHEMBL34513 0.77 TDP1 (0.52) ELANEPGRADRA2AADRA2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101228124-A Molecular modification of biological source compound and method for weeding UNIV NANJING AGRICULTURAL (CN) 2008-07-23 CN claimed
CN-1024011-C Process for producing cephalosporin compound TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1994-03-16 CN disclosed
CN-87101581-A Process for producing cephalosporin compound 1987-09-30 CN disclosed
CN-85105977-A The preparation method of antimicrobial compounds 1987-02-25 CN disclosed