Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | DBH | P09172 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316411 | 0.84 | KDM4E (0.47) | LMNACES2CES1PGRADRA2A | |
| SCHEMBL21456599 | 0.83 | KDM4E (0.43) | LMNACES2CES1PGRADRA2A | |
| SCHEMBL1714628 | 0.81 | CES2 (0.37) | LMNACES2CES1GSK3BL3MBTL1 | |
| SCHEMBL17201709 | 0.81 | SPHK1 (0.32) | LMNACES2CES1PGRADRA2A | |
| SCHEMBL27338904 | 0.80 | ELANE (0.33) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL28131090 | 0.80 | KMT2A (0.36) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL27262005 | 0.80 | ELANE (0.33) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL28318760 | 0.77 | HSD17B10 (0.38) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL9651524 | 0.77 | LMNA (0.39) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL27601754 | 0.77 | SLC7A5 (0.38) | LMNAPGRADRA2AADRA2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1860165-B | Flame retardant compositions | CIBA SC HOLDING AG | 2010-04-14 | — | — | CN | disclosed |
| CN-1860165-A | Flame retardant compositions | CIBA SC HOLDING AG (CH) | 2006-11-08 | — | — | CN | disclosed |