Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.34 |
| ▸ | GLRB | P48167 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726893 | 0.88 | ADORA2A (0.36) | PIK3CBGLRA3GLRBTGFBR1EEF2K | |
| SCHEMBL2726265 | 0.85 | TGFBR1 (0.38) | PIK3CBGLRA3GLRBTGFBR1NPC1 | |
| SCHEMBL2728038 | 0.82 | KDM4B (0.39) | PIK3CBGLRA3GLRBTGFBR1NPC1 | |
| SCHEMBL2726899 | 0.82 | ADORA2A (0.36) | PIK3CBGLRA3GLRBTGFBR1NPC1 | |
| SCHEMBL2725903 | 0.81 | PIK3CB (0.36) | PIK3CBGLRA3GLRBTGFBR1HCRTR1 | |
| SCHEMBL2729187 | 0.81 | CHEK2 (0.37) | PIK3CBTGFBR1EEF2KNPC1RAB9A | |
| SCHEMBL2728332 | 0.78 | KDM4E (0.39) | PIK3CBTGFBR1NPC1RAB9A | |
| SCHEMBL3648919 | 0.78 | PIK3CB (0.36) | PIK3CBGLRA3GLRBNPC1ALDH1A1 | |
| SCHEMBL2728011 | 0.78 | PDE10A (0.53) | TGFBR1NPC1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL2724726 | 0.77 | PARP1 (0.39) | PIK3CBGLRA3GLRBEDNRABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |